ELC unveils company's latest dermatological research at 81st SID Annual Meeting

ELC unveils company s latest dermatological research at 81st SID Annual Meeting

This month, the Estée Lauder Companies Inc. (ELC) presented an array of innovative research findings at the 81st Annual Meeting of the Society for Investigative Dermatology (SID) in Dallas, Texas. The event brought together leading experts in dermatology to explore the latest scientific developments, with ELC showcasing pioneering studies that could have notable future of skin care and personal care products.

Key research highlights

Cosmetic peptide penetration and assembly in human skin: A tag-free approach

Elham Tavasoli, PhD, Associate Director of Advanced Technology Pioneering at ELC, presented groundbreaking research on cosmetic peptide penetration. As detailed in ELC’s press release, “this is the first use of 3D OrbiSIMS and SRS to identify, track, and demonstrate the hierarchical assembly of cosmetic self-assembling peptides (SAPs) during skin permeation and their effect on skin mechanics,” and the study tracked the diffusion and hierarchical assembly of cosmetic peptides such as Palmitoyl-pentapeptide-4 and Palmitoyl-hexapeptide-12 in human skin.

The findings revealed significant enhancements in skin barrier function and hydration through the formation of stable hydrogels, marking a significant advancement in peptide-based skin care formulations. Specifically, “SAPs were shown to co-assemble into stable hydrogels when placed in contact with solutions of ECM components and chemical-specific imaging revealed skin barrier strengthening and increased water retention after SAP treatment,” the release confirmed. 

Dichotomous attributes of BHT, vitamin E, and vitamin C as antioxidant and anti-glycation molecules in skin models

Nora Ruth, MS, Principal Scientist at ELC, discussed the dual roles of BHT, vitamin E, and vitamin C as both antioxidants and anti-glycation agents. This study highlighted how varying concentrations of these antioxidants could inhibit glycation—a key factor in skin aging—thus providing valuable insights for developing personalized skin care solutions that address oxidative stress and glycation concurrently.

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