Researchers identify protein fragments for anti-aging cosmetic application

Researchers identify protein fragments for anti aging cosmetic application

Earlier this year, Professor Mike Sherratt of the University of Manchester, UK presented research findings at the American Academy of Dermatology conference which indicate certain protein fragments, or peptides, naturally produced by skin through the aging process, can potentially be isolated and applied topically to repair age-related damage like wrinkles.

Peptides are known to be released in response to UV damage or inflammation to support the skin’s natural repair process and have already been used as an ingredient in some cosmetic product formulations. In Sherratt’s research, his team used predictive artificial intelligence (AI) to isolate two peptides believed to be responsible for skin repair, then tested the efficacy of the peptides in topically applied patches.

The research team determined that the participants’ skin was ultimately more elastic after topical patch application due to increased levels of key protein structures when compared to untreated skin and noted that those increased levels were comparable to people several years younger than the participants age.

To learn more about Sheratt’s research and its potential impact for cosmetics and personal care product manufacturers, including the ways in which these findings can be applied to future product formulations, CosmeticsDesign interviewed Professor Sherratt and Dr. Ellie Bradley, Senior Scientist at the No7 Beauty Company for their insights.

CDU: Can you share some brief background about yourself, your organization, and your expertise in this area of research? 

Mike Sherrat (MS)​: I am a Professor of Biochemistry at the University of Manchester, one of the largest, most successful, and well-equipped research institutions in Europe. The collaboration with the No. 7 Beauty Company draws on extensive expertise in Manchester in extracellular matrix (ECM) biology and translational research in dermatology.

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